Idk if anyone has said anything but: I have a Quadro P5000 working with the 17 R1 (Ranger) running an i7-4940MX. Just had to switch to IGFX on a 60Hz display to make the power draw consistent at 95-100w, and modify my drivers using NVInstall (Check device manager and see if your card is trying to call for a different device ID, it'll guide you to the right P5000 to select when adding hardware support, they're definitely different in terms of what's installed) and boom, it worked no issues. Also worth using one of the OC bios's you can find on TechPowerUp's database, or use a hardware flasher to flash the iMac OC bios from the mac forums. Also on LVDS