Honestly, I have no experiences with running daily LTSC edition of Windows, except on vending machines, terminals etc.
My installation has been optimized & stripped of unnecessary crap afterwards (WinUtil + Group Policies + StartAllBack), of course it cannot be compared to a LTSC, but I am satisfied with the thing as it is. TBH, the only serious bug that I have encountered with the recent 25H2 so far, is the certain update switching drive letters between C and D and corrupting the bootloader in the process. Observed on multiple computers during the last month.
I understand the benefits of LTSC, but I am fine with normal Pro version. Once the hardware runs properly, the software I can live with. For example, the desktop machine in my signature has the same OS with exactly same mods / adjustments, and its running like a dream.